爱玩客

Chinese scientists develop electrode coating to address signal loss and tissue adhesion problems in long-term brain-computer interface implantation_我的网站

A |     

    Photo: VCG
Chinese researchers have developed a multifunctional electrode coating that addresses key challenges in long-term brain-computer interface (BCI) implantation, including signal loss and tissue adhesion, bringing BCI one step closer to clinical application, the Global Times learned from the research team behind the findings on Sunday. 
As an emerging field combining neuroscience and artificial intelligence (AI), BCI faces a major challenge of ensuring long-term compatibility between electrodes and brain tissue. Previous clinical trials showed that immune responses could cause implanted electrodes to retract after just three months, severely reducing signal quality and the number of available channels. 
This problem stems from chronic inflammation triggered by implants, which creates insulating scar tissue around electrodes and separates them from neurons. Irreversible adhesion between electrodes and brain tissue after long-term implantation also makes device removal risky, potentially causing brain injury during follow-up surgeries.
Experiments showed that flexible neural electrodes coated with this material could operate stably in the brain for more than 300 days and could be safely removed without causing damage. This means the universal coating technology can make electrodes not only operate stably over the long term but can also be safely removed and replaced after aging, paving the way for long-term BCI applications.
Developed by the research team led by Zhang Wei at the Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, associated with Beijing Tiantan Hospital, Shanghai Institute of Microsystem and Information Technology and NeuroXess, a high-tech life science company specializing in BCI technologies, the cationic alternating peptide electrode coating preserves electrode flexibility and conductivity, while offering antibacterial, anti-protein adsorption and immune-rejection-inhibiting functions. 
A 300-day animal study showed the coating's effectiveness. Bare electrodes experienced a sharp loss of recording capability after 90 days of implantation and could barely detect neuronal signals after 300 days. In contrast, coated electrodes maintained stable recording channels and consistently captured neural signals above 155 microvolts. 
In terms of neural modulation, after 300 days of implantation, conventional electrodes required a current of 100 microamps to induce weak limb responses, while coated electrodes triggered clear movements with only 2 microamps, improving modulation efficiency by 50 times. 
Notably, the removal tests highlighted a key advantage of the coating that electrodes no longer form irreversible bonds with brain tissue. In the experiments, the coated electrodes were removed intact, with minimal damage to the surrounding brain tissue, Zhang told the Global Times on Sunday.
。    每日商报讯 台风过境，本已偃旗息鼓的高温又重振旗鼓，昨天，杭城迎来久违的阳光，主城区跃上35.7℃，高温叠加高湿，有种重回“黄梅天”的错觉。不过，台风残涡并未就此作罢，“尾巴”还将持续洒水。截至昨日19时，杭州市主城区、临平区、临安区等多地发布暴雨黄色预警，余杭区发布暴雨红色预警。

B | 为什么明明台风已经停编，却还在大面积“洒水”？市气象台解释，从卫星云图上来看，“白海豚”的残余环流结合了西风槽以及台风的尾流，共同组合成为范围广阔的降水系统。而在天气形势图上，这片降水系统的东边和西边都是高压系统，导致降水系统相对较为稳定。

C | 受其影响，杭州在短期之内多雨的天气格局不会改变。值得注意的是，接下来强降雨还可能会杀个“回马枪”。这是因为，“白海豚”的尾流里西南季风和高压底部的东南气流交汇，还将催生出新的低压系统，未来“白海豚”的残余低压缓慢东移，与东边新生低压逐渐靠近，进一步增强杭州上空的辐合上升运动，加上季风源源不断输送水汽，预计今明两天杭州的降雨量将会明显增大，局地可能出现短时强降水、雷雨大风等强对流天气。好在，等这波雨水过去，本周日将迎来降雨暂歇，全省以多云到阴为主，部分有阵雨或雷雨，算是难得的“中场休息”。另外，台风还在扎堆生成，今年第17号台风“浪卡”（热带风暴级;英文名称Nangka;名字来源:马来西亚;名称意义:又名菠萝蜜果，黄色椭圆形状，是马来西亚非常流行的一种水果）于昨天上午在西北太平洋洋面上生成，下午5时许位于距离日本东京东南方向约1510公里的海面上，预计将以每小时30—35公里的速度向东北方向移动，未来“浪卡”对我国无影响。可以说，8月以来台风似乎无间断，如此密集生成是不是有点反常？其实，西北太平洋和南海一年四季都可能有台风生成，7月至9月是台风活跃季，8月台风生成的数量与登陆我国的个数均居于全年首位。8月平均有5.63个台风生成，其中2.3个登陆我国。近期台风密集，总体也符合常年规律，历年8月台风生成数最多的是1960年，多达14个。

Current article:http://cx4ox4.ruandaimingyunsun.sbs/m7jphaz/20260826/8782170.html

Published on:20:19:34